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LOW-MOLECULAR-WEIGHT HEPARIN-ASSOCIATED MULTIPLE DIGITAL NECROSIS IN A PATIENT AS A RESULT OF HEPARIN-INDUCED THROMBOCYTOPENIA SYNDROME
FATİH KABAKAS, MERİC UGURLAR, OZGE YAPİCİ UGURLAR, YESİM BİCER
İstanbul Kuzey Klinikleri Dergisi - 2021;8(4):402-404
Department of Hand Surgery, Gebze Medical Park Hospital, Kocaeli, Turkey

Heparin-induced thrombocytopenia syndrome (HITS) is a rare complication of low-molecular-weight heparin (LMWH). It is an autoimmune-mediated side effect of LMWH which is caused by platelet-activating antibodies that recognize platelet factor-4/heparin complexes. Although HITS often leads to thrombosis in large veins and arteries, it can be presented as microvascular thrombosis. In this article, we report a case of HITS complicated with multiple digital necrosis after administration of LMWH.

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