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COMPARISON OF PUNCH AND LOOP BIOPSY IN PATIENTS WITH HIGH-GRADE SQUAMOUS INTRAEPITHELIAL LESION

VAROL GÜLSEREN KEMAL GÜNGÖRDÜK

Türk Jinekolojik Onkoloji Dergisi - 2023;23(2):37-42

 

Objective: It was aimed to compare and evaluate the performance of cervical punch and loop biopsy. Methods: Patients who were found to have high-grade squamous intraepithelial lesion (YDSIL) as a result of Pap smear between 2019-2020, and who underwent colposcopy and biopsy were included in the study. The clinical data and demographic characteristics of the patients were evaluated by retrospective file scanning. Patients who had 56 punch biopsy (PB) and 51 Loop cervical biopsies were included in the study. Results: The mean age of the patients was 35.3 ± 8.2 and 37.6 ± 10.5 in the PB and Loop groups, respectively, and no significant difference was found in the results (P= 0.208). While 21.4% of the patients in the PD group were nulliparous, 21.6% of the patients in the Loop group were nulliparous (P= 0.571). The mean specimen width was 4.9 ± 1.2 mm and 11.0 ± 1.7 mm in the PB and Loop groups, respectively (P< 0.001). It was shown that the specimen depth was shorter in the punch biopsy group (3.9 ± 0.7 for PB, 6.6 ± 1.0 for Loop; P< 0.001). Minimal hemorrhages were found at similar rates in both groups (8.9% for PB, 9.8% for Loop). When patients were questioned about pain during the procedure, no difference was found between the groups (5.8 ± 1.3 for PB, 6.2 ± 1.8 for Loop; P= 0.206). Total tissue score was calculated using 3 parameters. It was analyzed that there was no difference between the groups in terms of tissue adequacy (including epithelium + stroma). Conclusion: Although the specimen depth and width were longer in the Loop group and there was cautery artifact, tissue adequacy, bleeding and pain scores were found to be similar between the PB and Loop groups. The superiority of the two biopsy methods over each other has not been proven