ROWAN KLEİN NULEND, ANİMESH SİNGLA, RAMESH DE SİLVA, JASVEEN RENTHAWA, LAWRENCE YUEN, JEROME MARTİN LAURENCE, TAİNA LEE, HENRY PLEASS
Experimental and Clinical Transplantation - 2022;20(8):771-775
Cytomegalovirus infection after transplant has been dramatically reduced in the modern era with improved understanding of immunosuppression and perioperative transplant care. However, cytomegalovirus syndrome with or without tissue invasive disease can still lead to significant morbidity and mortality. Several organs can be involved: most commonly, the gastrointestinal tract, liver, pancreas, lung, and the transplanted renal allograft. Postoperative cytomegalovirus colitis after renal transplant is well recognized and described, with symptoms including abdominal pain, nausea, and diarrhea. Biochemistry can demonstrate pancytopenia with a leukopenia with or without histopathology confirmation. A high index of suspicion is required for a timely diagnosis. This is the first published case report of a patient with cytomegalovirus tissue invasion presenting with a perianal fistula and abscess formation. The diagnosis and management of this case with a literature review is discussed.
