MUSTAFA TİMURKAAN, ESRA SUAY TİMURKAAN, GÜLSÜM ALTUNTAŞ
Annals of Clinical and Analytical Medicine - 2023;14(2):167-172
Aim: In stroke patients, there is a close relationship between the inflammatory response and poor prognosis. In this study, we aimed to compare the prognostic roles of NLR and CAR in ischemic stroke patients. In addition, we planned to formulate NLR with CRP and Albumin and to investigate the superiority of this parameter in predicting mortality and prognosis. Material and methods: Patients with the diagnosis of ischemic stroke in the tertiary intensive care units were retrospectively evaluated between August 2018 and October 2022. NIHSS, GCS, APACHE II scores, demographic data, comorbidities, treatment regimens, laboratory, and clinical variables were obtained from the hospital database. The IPI was calculated as C-reactive protein × NLR (neutrophil/ lymphocyte ratio)/serum albumin. CAR, NLR, PLR, and IPI were compared by ROC curves. Results: Of the 660 patients in the study, NIHSS, APACHE II, CAR, NLR, PLR, and IPI constituted a risk for mortality in the multivariate analysis. AUC for CAR: 0.968, NLR: 0,980 PLR: 0,923, IPI: 0,984. Discussion: Increases in NLR, PLR, CAR, and IPI correlate with mortality in ischemic stroke patients. The IPI parameter can be used safely and easily, like the other combined parameters such as CAR, NLR, and PLR.
