SEYDA GURAY EVİN, AHMET BİLİRER, OSMAN AKDAG, MEHTAP KARAMESE
Türk Plastik, Rekonstrüktif ve Estetik Cerrahi Dergisi - 2018;26(1):37-39
Epidermodysplasia verruciformis (EV) (Lewandowsky-Lutz syndrome) is a genodermatosis that accommodates premalignant skin lesions extensively infected with human papillomavirus with underlying cellular and humoral immune disorders. Localized especially in regions extensively exposed to the sun such as the forehead, these skin lesions may turn into malignant lesions with the mutation-inducing effect of ultraviolet lights. The skin lesions that may emerge as a result of this transformation include actinic keratosis, Bowen’s disease, squamous cell carcinoma (SCC), and more rarely basal cell carcinoma. The SCC that develops in patients with EV may act aggressively and can become locally invasive. This article aims at presenting the underlying EV as a rare etiological cause in patients with SCC at an early age.
