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ADMINISTERING RIASTAP FOR CONGENITAL AFIBRINOGENEMIA DURING LIVER TRANSPLANT

CHRİS GİORDANO, CHRİS JOHNSON, JANİCE LAWSON, ANİTA RAJASEKHAR, ELİZABETH THOMAS

Experimental and Clinical Transplantation - 2021;19(3):269-272

Department of Anesthesiology, University of Florida College of Medicine, Gainesville, Florida, USA

 

Liver transplant has occasionally been performed in the presence of congenital afibrinogenemia and has been rarely used to treat it. Historically, to safely manage coagulopathy during transplant, these patients have been administered a combination of fresh frozen plasma and cryoprecipitate. In this case report, we discuss the first reported use of recombinant fibrinogen to treat such a patient and the decision-making process considered to balance the thrombotic and hemorrhagic risks.