Prairna BALYAN, Ahmad ALI
Acta Pharmaceutica Sciencia - 2024;62(3):498-514
The COVID-19 pandemic has prompted researchers to look for novel compounds with SARS-CoV-2 antiviral potential. Numerous studies have demonstrated that natural compounds have potent antiviral properties. This review suggests potential natural products and their isolates for treating human coronaviruses based on effective herbal treatments for coronavirus infections. Given the effects of human coronavirus strains, finding alternative isolated compounds from plants (like anthraquinones and coumarin) that could prevent viral infection will aid in hastening the medication discovery process. It is known that anthraquinone derivatives have immune-stimulating, anti-inflammatory, and antiviral properties. Coumarin, a naturally occurring compound, is also a promising therapeutic candidate because of its solubility, stability, and low toxicity. These natural substances may interfere with target-specific proteins to stop viral replication in the host. Natural remedies not only stop viruses from attaching to the host body but also stop them from reproducing and strengthen the host"s immune system.
