SUSİ NOVARYATIIN, SYAHRİDA D ARDHANY, MUHAMMAD T RAHMAN, MUHAMMAD D MUTTAWALI, HİKMAH HIKMAH, ELİN TRI, FAHRUDDİN ARFIANTO, NANANG HANAFI
Acta Pharmaceutica Sciencia - 2023;61(1):37-48
The C. javanicum Blume is a typical plant that can be founded in Central Kalimantan. This research aimed to find out the total flavonoids, alkaloids, tannins, and compounds and to evaluate the antioxidant and antibacterial activity of ethanol extract of the stem of C. javanicum. The antioxidant activity was tested by two different assays: DPPH and FRAP. Total alkaloids, flavonoids and tannins content were 32.81±0.77 µg caffeine equivalent/mg, 126.96±3.17 µg quercetin equivalent/ mg, and 42.89±0.77 µg catechin equivalent/mg, respectively. The IC50 value of DPPH was 20.63±0.82 ppm quercetin equivalent while the FRAP method was 968.38±22.25 µmol trolox/g. C. javanicum extract had antibacterial potential against the three bacteria tested, with the inhibition zones in the range of 3.17±0.90 - 8.90±1.50 mm. It can be stated that the ethanol extract of the stem of C. javanicum has high potential antioxidant activity, however, the antibacterial activity is classified as weak activity.
