Ahmet DÜZGÜN, Seher YANATMA, Maşallah ÇAKIRER, Burhan Sami KALIN
Türk Yoğun Bakım Dergisi - 2026;24(2):134-140
Objective: To evaluate the prognostic value of arterial pH at ICU admission for short-term survival after cardiac arrest. Materials and Methods: This single-center observational study included 60 adults (>=18 years) admitted to the ICU between May 2024 and June 2025 after successful resuscitation with return of spontaneous circulation (ROSC). Clinical, demographic, and laboratory data were collected. Survivors and non-survivors at day 7 were compared using logistic regression and ROC analyses to determine independent predictors of mortality. Results: The mean age was 61 +/- 17 years, and 43% of patients were women. Seven-day mortality was 51.7%. Non-survivors were older and had higher APACHE II scores, lactate and procalcitonin levels, longer CPR-to-ROSC intervals, lower arterial pH values, and shorter ICU stays (all p < 0.05). In multivariable logistic regression analysis, age, higher APACHE II score, elevated procalcitonin levels, and lower arterial pH were independently associated with 7-day mortality. Lower arterial pH remained significantly associated with mortality (OR: 1.53; 95% CI: 0.93-2.86; p = 0.044). ROC analysis yielded an AUC of 0.668, with an optimal pH cut-off value of 7.13 (sensitivity 61.3%, specificity 75.9%). Conclusion: Lower arterial pH at ICU admission independently predicts 7-day mortality after cardiac arrest, emphasizing the importance of early recognition and correction of acidosis in post-resuscitation care
