Ekin SAY, Özlem ÜZÜM, Tolga İNCE, Belgin ÜNAL, Adem AYDIN
Annals of Clinical and Analytical Medicine - 2026;17(10):1005-1010
Aim: Lactose intolerance is a clinical condition that affects both the infant and the family physically and mentally, and can also be seen in infants, adults, and children. Diagnosis is more difficult in infants than in children and adults. In this study, we aimed to assess 113 infants, aged 0-6 months, who respond to treatment, have lactose intolerance symptoms, and have received oral lactase treatment. Methods: 113 infants aged 0-6 months with lactose intolerance, clinical symptoms, and positive stool-reducing substances who had started receiving oral lactase treatment were included in the study. The patients' demographic characteristics, symptoms, and lactase enzyme use were recorded and compared using appropriate statistical methods. Results: It has been determined that 86.7% of infants utilize the lactase enzyme. No differences have been observed in birth weight, birth week, or gender in the utilization of the lactase enzyme. It has been observed that the longer the lactase enzyme utilization period, the greater the benefit ( P = .01). No significant difference has been observed when the stool-reducing substance and stool pH level are compared to the utilization of the lactase enzyme. Conclusion: The lactase utilization of infants with lactose intolerance who have clinical symptoms, positive stool-reducing substances, and who use lactase does not vary by gender, birth weight, or birth week. The utilization increases as the treatment period extends.
