SEVDA SAGLAMPİNAR KARYAGAR, SAVAS KARYAGAR, SERAY SARACOGLU, BİNNUR DONMEZ YİLMAZ
Eurasian Journal of Medical Investigation - 2021;5(2):218-224
bjectives: To analyze the rates, patterns, and features of bone metastases(BM) detected using 18F-FDG PET/CT in pa tients with colorectal cancer(CRC) and compare them with bone scans (BS) in terms of BM detection. Methods: A total of 920 patients with CRC who underwent 18F-FDG PET/CT scans during the period from Jan 2016 to May 2019 were retrospectively reviewed. Among these, imaging results were compared for 29 patients who underwent BS within 1 month of 18F-FDG PET/CT. Results: In 38(4.1%) patients, 211 BM were detected on 18F-FDG PET/CT imaging. Of 211 BM detected by PET/CT, 42 were osteolytic, 30 were osteoblastic, 55 were mixed, and 84 were CT-negative. Mean SUVmax values of osteoblastic, CT-negative, osteolytic, and mixed lesions were 6.05±2.80, 5.42±2.56, 11.62±6.34 and 8.74±4.48, respectively. A total of 126 BM were detected in 16 of 29 patients who underwent both BS and PET/CT imaging. In patient-based evaluation, the sensitivity, specificity and accuracy of PET/CT and BS were 100%, 76.92%, 89.66% and 93.75%, 46.15%, 72.41% and in lesion-based evaluation these values were 99.21%, 72.73%, 97.08% and 52.38%, 0%, 48.18%, respectively. Conclusion: 18F-FDG PET/CT is a valuable imaging method for detecting BM in colorectal cancer patients, especially since it can truly detect CT-negative or isolated BM. BS is not required for patients who have undergone PET/CT imaging.
