ADEM SENTURK, ALP OMER CANTURK, FULDEM MUTLU
Annals of Clinical and Analytical Medicine - 2024;15(11):784-788
Aim: High levels of fibrinogen and low levels of albumin are associated with ischemic vascular diseases. This study aims to investigate whether the levels of serum fibrinogen and albumin, FAO, and prognostic nutritional index (PNI) effectively predict prognosis in acute mesenteric ischemia. Material and methods: Patients treated in our clinic with the diagnosis of Acute mesenteric ischemia (AMI) between 2013 and 2023 were evaluated for inclusion. Patients were divided into two groups: those who were alive after the first month (group 1) and those who died within the first month (group 2). The investigated parameters were statistically compared between these groups. Results: We included 39 patients in this study. Twenty-one of the patients (53.8%) were alive one month after the surgery (group 1), whereas 18 patients (46.2%) died (group 2). The difference in the mean ages of patients in both groups was not statistically significant (74.6±9.2 and 69.4±10.6, respectively; p=0.114). Group 2 had higher fibrinogen levels compared with group 1 (524.0±165.7 mg/dL vs. 427.8±114.0 mg/dL; p=0.039). Albumin levels were similar between the two groups (3.0±0.6 g/dL vs. 2.8±0.5 g/dL; p=0.179). The mean FAR value was significantly higher in group 2 (198.5±76.9 vs. 149.8±56.9; p=0.029). FAR in 71.8% of them with the optimal cut-off value >157.6 (AUC= 0.688, p= 0.033). PNI was not successful in predicting mortality (AUC=0.605, p=0.189) Discussion: The present study proposed that the FAO could be a new and valuable prognostic marker in patients with AMI, unlike PNI.
