SEVCAN SARIKAYA, İLENAY AYDIN, HASAN BEDRİ AYDIN, OĞUZHAN GÜNENC, EMRE UYSAL, ALPAY TUNCAR
Comprehensive Medicine - 2023;15(3):226-233
INTRODUCTION: In this study, we looked at the impact of the systemic immune-inflammation index (SII), the neutrophil/lymphocyte ratio (NLR), and the platelet/lymphocyte ratio (PLR) in predicting postpartum depression (PPD). METHODS: Age, body mass index, educational attainment, marital status, smoking, and other demographic details of patients who attended the regular outpatient clinic control in the third trimester were noted. The Beck Depression Inventory in the third trimester and Edinburgh PPD Scale (EPDS) in the 1st month postpartum were applied to the patients. PLR, NLR, and SII were calculated from the whole blood test performed at the time of delivery. Patients with EPDS score ≤11 (Group I=210) were considered to have no risk of PPD. Patients with an EPDS score >11 (Group II=190) were considered to have PPD risk. Demographic data and parameters obtained from complete blood count of these two groups were compared statistically. Results: When both groups were compared, their demographic characteristics were similar (p>0.05). The mean NLR, PLR, and SII values of Group II were significantly higher than Group I (p<0.05). Beck Depression Scale mean score did not differ significantly between the two groups (p>0.05). DISCUSSION AND CONCLUSION: Significant efficacy of NLR, PLR, and especially SII was observed during pregnancy in predicting PPD. Patients with high these values should be followed closely in terms of PPD.
