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CATASTROPHIC ANTIPHOSPHOLIPID SYNDROME: A CASE WITH UNUSUAL FINDINGS REVEALED IN AUTOPSY AND A BRIEF LITERATURE UPDATE

FLAVİO SİGNORELLİ, GUSTAVO GUİMARÃES MOREİRA BALBİ, ROGER A LEVY

European Journal of Rheumatology - 2017;4(4):281-283

Department of Internal Medicine, Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil

 

Catastrophic antiphospholipid syndrome (CAPS) is a rare and life-threatening disease. It is characterized by multiple arterial and/or venous thrombotic events, including the microcirculation, occurring in a short period, and can affect any system. Catastrophic antiphospholipid syndrome can occur in individuals with known APS under treatment, or it can be its first manifestation; in most cases, there is a triggering factor that can be identified. In this case report, we report a case of CAPS with multiple thromboses at unusual sites, including the lungs, coronary arteries, stomach, thyroid, gastrocnemius muscles, lymph nodes, and bladder, in a patient with previous diagnosis of systemic lupus erythematosus.