CLINICAL DETERMINANTS OF IN-HOSPITAL MORTALITY IN A MULTICENTER CORONARY CARE UNIT COHORT

İbrahim ERSOY, Ahmet Seyda YILMAZ, Fatih KAHRAMAN, Gökay TAYLAN, Emin Erdem KAYA, Ertan AYDIN, Muammer KARAKAYALI, Muhammed Mürsel ÖĞÜTVEREN, Aybike Gül TAŞDELEN, Siho HİDAYET, Ömer KUMET, Murat GÜL, Alpin Mert TEKİN, Serdar Gökhan NURKOÇ, Şeyhmus ATAN, Mehmet ÖZGEYİK, Çağlar KAYA, Oğuz KILIÇ, Aslıhan Merve TOPRAK, Mehmet ÖZBEK, Ömer KERTMEN, Özgen ŞAFAK, Gurbet Özge MERT, Şahin TOPUZ, Mehmet Koray ADALI, Mevlüt DEMİR, Faruk KARA, Mürsel ŞAHİN, Feyza KURT, Fulya Avcı DEMİR, Sefa Erdi ÖMÜR, Mehtap YENİ, Mustafa Beğenç TASANOV, Yunus Emre YAVUZ, İdris Buğra ÇERİK, Şaban KELEŞOĞLU, Yücel KAÇMAZ, Adem ATICI, Melisa UÇAR, İshak YILMAZ, Sevil GÜLAÇTI, Burak ACAR, İsmail Barkın IŞIK, Ramazan DÜZ, İbrahim Halil TANBOĞA

Interventional Cardiology Perspectives - 2026;2(2):40-48

Clinic of Cardiology, Kepez State Hospital, Antalya, Türkiye

 

Background: Cardiovascular diseases remain a major global health concern, and coronary care units (CCUs) provide specialized care for patients with acute cardiovascular conditions. Objective: This multicenter cohort study aimed to investigate mortality rates in Turkish CCUs and identify predictors of in-hospital mortality. Study Design: Multicenter, observational cohort study. Methods: Patients admitted to CCUs across Türkiye with cardiovascular diagnoses were included. Demographic, clinical, laboratory, and outcome data were collected. Regression analyses were performed to identify predictors of in-hospital mortality. Results: A total of 3,157 patients were included, and the overall CCU mortality rate was 4.3% (n=137). The median age was 65 years (interquartile range, 56-73), and 66.1% of the patients were male. Hypertension (59.8%) and diabetes mellitus (37.5%) were the most common comorbidities. Non-survivors had significantly higher rates of heart failure and chronic kidney disease and lower ejection fractions than survivors. Age, female sex, lower mean blood pressure (BP), elevated serum creatinine, C-reactive protein, and white blood cell count were independent predictors of in-hospital mortality. Mean BP and serum creatinine were the strongest contributors to mortality prediction. Conclusion: CCU mortality in Türkiye was relatively low. Hemodynamic impairment and renal dysfunction were the primary determinants of in-hospital mortality, highlighting the value of simple clinical parameters for early risk stratification.