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ADR Yönetimi
ADR Yönetimi

CLINICOPATHOLOGIC AND MOLECULAR ANALYSIS OF INFLAMMATORY PSEUDOTUMOR-LIKE FOLLICULAR/FIBROBLASTIC DENDRITIC CELL SARCOMA: A CASE REPORT AND REVIEW OF LITERATURE

BRYAN MORALES VARGAS, KRİSTİN DEEB, DENİZ PEKER

Türk Patoloji Dergisi - 2021;37(3):266-272

Department of Pathology and Laboratory Medicine, Emory University School of Medicine, GEORGIA, USA

 

Inflammatory pseudotumor-like follicular/fibroblastic dendritic cell (FDC/FRC) sarcoma is an extremely rare neoplasm of the spleen associated with EBV and characterized by spindle cell morphology, dense mixed chronic inflammatory background, and a broad immunophenotypic profile often causing a diagnostic challenge for pathologists. The molecular features of FDC/FRC sarcoma are largely unknown due to a lack of comprehensive data. Here we present the results of next-generation sequencing and Single Nucleotide Polymorphism Copy Number array analysis in a case of FDC/FRC and review the literature.