Fikriye Karanfil Yaman
Ankara City Hospital Medical Journal - 2025;4(4):133-137
Introductıon: The purpose of this article is to report a rare case of twin pregnancy complicated by a complete hydatidiform mole with a live fetus and to review the clinical challenges associated with its management. Case Presentation : A 21-year-old woman in her third pregnancy with a history of one previous birth and one miscarriage was referred to our terti - ary clinic at 21 weeks of gestation with a suspected molar pregnancy. Ult - rasonography revealed a dichorionic twin pregnancy consisting of a normal fetus and its anterior placenta, along with a posterior placental mass with a "bunch of grapes" appearance. Laboratory findings showed markedly ele - vated beta-hCG levels and suppressed TSH values. Amniocentesis confirmed a normal fetal karyotype, but concurrent mole tissue analysis was initially inconclusive. The pregnancy was closely monitored with weekly beta-hCG and ultrasound assessments. At 33+6 weeks, an emergency cesarean section was performed due to vaginal bleeding, and a male baby weighing 1750 g was born. Postnatal histopathology confirmed a complete hydatidiform mole in one placenta and a normal placenta in the other. Postpartum beta-hCG levels gradually decreased, and no evidence of gestational trophoblastic ne - oplasia was observed on follow-up. Conclusion : Twin pregnancy with a complete hydatidiform mole and a co - existing fetus is an extremely rare condition associated with significant ma - ternal and fetal risks. Careful monitoring t may allow favorable outcomes in selected cases where continuation of pregnancy is chosen.
