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COMPARISON OF METHODS USED FOR FINAL HEIGHT PREDICTION IN PATIENTS WITH CENTRAL PRECOCIOUS PUBERTY

Nisa Nur TURAN, Aşan Önder ÇAMAŞ, Burçin ÇİÇEK, Merve Nur HEPOKUR, Hamdi Cihan EMEKSİZ

Journal of Clinical Research in Pediatric Endocrinology - 2026;18(1):66-73

İstanbul Medeniyet University, Göztepe Prof. Dr. Süleyman Yalçın City Hospital, İstanbul

 

Objective: Various methods may be used to estimate target height in patients diagnosed with precocious puberty. These methods include the Bayley-Pinneau (BP) and Roche-Wainer-Thissen (RWT) methods. In addition to these methods, in our clinic, we routinely use a practical approach based on the percentiles in growth charts. In this method, the bone age percentile is projected to the end of the percentile curve (at 18 years of age) to estimate the final adult height. We have named this method Bone Age Percentile Curve Projected Height Estimation (BAPCPHE). The aim of this study was to retrospectively compare the effectiveness of these three methods in predicting target height in patients treated for central precocious puberty and who have reached their final height in our pediatric endocrinology clinic. Methods: Fifty female patients were included. The predicted adult heights (PAH) were calculated at treatment initiation, at the end of the first, second, and third years of treatment, and at the time of final height attainment using the BP , RWT, and BAPCPHE methods, based on the patients' heights and bone ages.