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COMPARISON OF PATIENTS’ COMPLIANCES, TOLERANCES, AND EXPERIENCES OF DIFFERENT COLONOSCOPIC BOWEL PREPARATION AGENTS: A PROSPECTIVE OBSERVATIONAL STUDY

ŞENDAĞ ALKAN, SENNUR KULA ŞAHİN

Turkish Journal of Colorectal Disease - 2023;33(3):64-71

 

Aim: Patients’ compliance and tolerance in terms of bowel cleansing agents and quality of bowel cleansing are important for a successful colonoscopy procedure. Method: This is a prospective observational study that was conducted to compare the compliances, tolerances, and experiences of patients in whom polyethylene glycol (PEG), macrogol, and sennoside + enema agents were used for bowel cleansing before colonoscopy. The sample was composed of a total of 159 patients who received PEG (n=53), macrogol (n=53), and sennoside + enema (n=53) in the endoscopy unit in a university hospital in the province of Adana between March 1, 2020, and July 15, 2020. The “Descriptive Characteristics Form”, which was developed by the researchers, and the “Colonoscopy Patient Assessment Form” and “Colonoscopy Procedure Assessment Form,” which interrogated compliance, tolerance, and bowel cleansing quality and the patients’ experiences, were used for data collection. Results: In this study, compliance (p=0.115), bowel cleansing qualities (p=0.827), and experiences (p>0.05) were found to be similar in the patients in the three groups. However, it was found that the patients in the sennoside + enema group developed intolerance including nausea (p=0.039), vomiting (p=0.045), and malaise and fatigue (p=0.042) to a greater extent and needed more help (p<0.001) compared with the patients in the macrogol and PEG groups. Half of the patients (47.3%) described the bowel preparation for colonoscopy as tiring and wearing. Conclusion: Sufficient bowel cleansing was provided with all three bowel cleansing agents used before colonoscopy in this study. The patients tolerated the PEG solution better than the sennoside + enema and macrogol agents. Comprehensive prospective randomized studies with large sample sizes are needed to better evaluate the effect of bowel cleansing agents and to help patients have a more comfortable colonoscopy procedure.