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COMPARISON OF THE NEUTROPHIL LYMPHOCYTE RATIO IN THE INFLAMMATORY RESPONSE WITH IMMIGRANT AND NON-IMMIGRANT CRITICAL PATIENTS

MEHMET KÖSEOĞLU, İBRAHİM AKKOÇ, MEHMET TOPTAŞ, MAZLUM ŞAHİN, SELMAN YENİOCAK, ASLIHAN YALÇIN, HİDAYET NEDRET ERGÜVEN

Comprehensive Medicine - 2024;16(3):142-146

Department of Anesthesia, University of Health Sciences, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, İstanbul, Türkiye

 

INTRODUCTION: Global mobility has heightened the necessity to addressing racial diversity in healthcare. Recognizing variations that influence diagnosis and treatment can enhance patient outcomes. We aimed to assess if the Neutrophil Lymphocyte Ratio (NLR) reflects inflammation differently in Arab-origin immigrant patients admitted to the Anaesthesia Intensive Care Unit (ICU) compared to non-immigrants. METHODS: This retrospective, single-center study examined ICU records from January 2011 to January 2014. Patients were categorized as Turkish or Arab immigrants. Exclusions comprised patients under 18, those deceased within 24 hours of admission, malignancy cases, systemic steroid users, and those with immunosuppressive histories. A total of 100 patients over 18 were analyzed. Results: Of the 100 patients (63 men, 33 women), 49 were immigrants and 51 non-immigrants. No significant differences were found in CRP, neutrophil-lymphocyte count, or NLR upon admission. However, CRP and neutrophil counts differed significantly on culture-positive days (p<0.005). NLR did not significantly vary between the groups on culture-positive days. DISCUSSION AND CONCLUSION: No substantial association was observed between NLR levels in critically ill Arab-origin immigrants versus non-immigrants in the ICU. Larger studies and detailed genetic analyses are warranted to inform critical patient care.