MURAT KARS, MEHMET ÇETİN, MUHAMMED HASAN TOPER, DENİZ FİLİNTE, KAMİL ÇAM
Bulletin of Urooncology - 2024;23(3):73-77
Objective: The objective of this study was to assess the efficacy of urine cytology in predicting definitive pathology in patients undergoing transurethral bladder tumor resection. Materials and Methods: Patients who underwent transurethral bladder tumor resection between January 2019 and April 2022 were included. Urine cytology was performed via the bladder wash of the first urine sample as the initial procedure during cystoscopy. Then, transurethral resection of the bladder tumor was performed. The demographic characteristics of the patients, including age and sex, were recorded. The diagnostic accuracy of urine cytology for bladder tumor detection was calculated using the Paris System for Reporting Urinary Cytology. Results: A total of 229 patients who underwent endoscopic bladder tumor resection for urothelial carcinoma comprised the study group. Among patients, 193 (84.28%) were male and 36 (15.72%) were female. Urine cytology revealed “negative for high-grade urothelial carcinoma” in 44.11% of the patients, and “lowgrade urothelial carcinoma” in 27.31% of the cases as the most common first two findings. The definitive pathological examination after endoscopic surgery revealed benign histology in 23.75% of the patients, whereas the remaining patients had urothelial carcinoma. The overall efficacy of urine cytology in detecting urothelial tumors was 72.89% sensitivity and 90.47% specificity. Conclusion: Urine cytology can predict the final pathology of bladder urothelial carcinoma with limited sensitivity
