Ecem GÜRSES
Cardiovascular Surgery and Interventions - 2026;13(1):27-30
Objectives: To evaluate the predictive value of the Mehran score for contrast-induced nephropathy (CIN) following peripheral transcatheter angioplasty (PTA) in patients with peripheral artery disease (PAD). Patients and methods: We retrospectively analyzed 103 patients who underwent PTA at our center between January 2020 and July 2024. The Mehran score was calculated for all patients meeting inclusion criteria. CIN was defined as an absolute increase in serum creatinine >=0.5 mg/dL or a relative increase >=25% within 48-72 hours post-procedure. Receiver operating characteristic analysis was used to assess the predictive value of the Mehran score. Multivariate logistic regression identified independent risk factors for CIN. Results: CIN occurred in 19 patients (18.4%). Patients who developed CIN received significantly higher contrast volumes (p<0.05). The optimal Mehran score cut-off for predicting CIN was 11.2, with an area under the curve of 0.712 (95% confidence interval: 0.612-0.826; sensitivity 69%, specificity 73%). Independent predictors of CIN included advanced age, diabetes mellitus, higher contrast volume, baseline glomerular filtration rate, and the Mehran score. Patients with CIN had longer hospital stays (3.9+/-1.7 vs. 1.9+/-0.7 days, p=0.002) and higher amputation rates (10.6% vs. 2.9%, p=0.004). Conclusion: The Mehran score is a valuable tool for predicting CIN after PTA in PAD patients. Risk stratification using the Mehran score may guide preventive strategies, although PAD-specific models incorporating additional parameters are warranted.
