Marwan Muhammad Yousry, Muhammad Hosni Eldesoqy, Muhammad Almaadawy, Hussam Aldeen Anas, Ahmad Gamil Abdellattif, Alaa Eldin Mahmoud Lotfy
Turkish Journal of Vascular Surgery - 2025;34(3):242-247
Aim: Primary varicose vein is still one of the most prevalent venous disorders, faced daily in the surgical practice. Shifting from surgical intervention to endovenous interventions (thermal or non-thermal) is currently the standard practice because of their better results and patients' satisfaction. The aim of our study is to compare vein closure rate and overall venous thrombosis , 12 months after either Cyanoacrylate or endovenous laser treatment for Great Saphenous vein incompetence. Material and Methods: The study was a retrospective study analyzing the data of 126 lower limbs in 120 patients with Great Saphenous vein (GSV) incompetence who underwent either Cyanoacrylate closure ( CAC ) or Endovenous Laser Ablation ( EVLA ) and were followed for 12 months between Jan. 2022 and March 2025 . Vein closure and thrombosis rates were our primary endpoints. Sixty patients with 66 limbs had EVLA. We used ( VenaSeal, Medtronic ) for CAC and ( Ceralas E Biolitec 1470nm WL, ELVeS, Radial fiber Diode ) for EVLA. Results: A total of 126 lower limbs in 120 patients were treated, the atients were between 18 and 65 years old (mean age was 38 +/- 12 years) and 65% of them were females. They were followed for 12 months (48% had complete 12-month follow up). Vein closure rates were 100% in both modalities ( 1-month period ), 97% in EVLA and 100% in CAC-patients ( 6-month period ) and 94% in EVLA-patients and 96% in CAC-patients (12-month period ). It was found that 3% of EVLA-patients had Endovenous Heat Induced thrombosis (EHIT) and 2% of CAC-patients had Endovenous Glue Induced Thrombosis (EGIT) with no incidence of Deep Vein Thrombosis (DVT) during the follow up period . Conclusion: Cyanoacrylate vein closure results were not inferior to laser vein treatment in great saphenous varicose veins, nevertheless Cyanoacrylate surpassed Laser treatment in six and twelve-month vein closure rate . Both modalities were safe and free of major venous thrombosis.
