HALE KÖKSOY MOHAMMED SALEH AMEEN AL QADRİ SERAP KARAKAYA PELİN BACAK ELİF SENANUR YÜKSEL ŞENGÜL KOÇER EMİNE KAV SÜMEYRA DEMİR ECE DEMİREL HİMMET AKKAYA AYŞE NUR AKMEŞE AYŞENUR TAŞKAYA
Genel Tıp Dergisi - 2023;33(5):594-598
Aims: CRISPR/Cas9, a revolutionary genome editing tool derived from a bacterial system, has transformed molecular biology research, enabling precise and versatile modifications to the genome. This study surveyed 300 participants, including instructors, second-year medical students, and patient relatives from Selcuk University Faculty of Medicine, to assess their knowledge, attitudes, and ethical perspectives on gene editing. Methods: A comprehensive survey was conducted, and the participants’ demographics were correlated with their responses. Statistical analysis was performed using SPSS 22.0. Results: The survey revealed significant differences (p<0.05) in attitudes based on gender, age, and participation groups. The age group of 18-29 exhibited the highest participation rate (57.3%), while the age group of 60-65 had the lowest (1%). Approximately 50.3% of participants reported no prior knowledge of CRISPR/Cas9, and 64.3% were university graduates. Obtaining approval from ethics committees was considered crucial by 151 respondents for commencing CRISPR/Cas9 research. Interestingly, 63.3% showed eagerness for genetically modified plants and animals, while only 9% expressed interest in studies related to eternal youth. Additionally, 88% found gene editing studies conflicting with their beliefs. Conclusions: CRISPR/Cas9 holds great promise for biomedicine and healthcare but necessitates enhanced public awareness and informed decision-making. The study highlights the importance of promoting informed discussions on the ethical implications of CRISPR/Cas9 to address the concerns and perceptions of various demographics. These valuable insights contribute to the ongoing discourse on the impact of CRISPR/Cas9 on society.
