DOES HELICOBACTER PYLORI INFECTION AFFECT INDIRECT HEPATIC FIBROSIS TESTS?

ALİ CAGATAY BOZKİNA, GOKSEL BENGİ, SULEYMAN DOLU, ANİL AYSAL, MUJDE SOYTURK, ENDER BERAT ELLİDOKUZ, OMER SELAHATTİN TOPALAK, HALE AKPINAR, MESUT AKARSU

Hepatology Forum - 2025;6(3):105-110

Department of Internal Medicine, Dokuz Eylul University School of Medicine, Izmir, Turkiye

 

Background and Aim: Early detection, accurate evaluation, and proper follow-up of fibrosis in chronic liver disease are crucial for improving disease prognosis. Indirect biochemical fibrosis tests, such as the AST-toPlatelet Ratio Index (APRI) and Fibrosis-4 (FIB-4) score, have been developed, incorporating parameters like AST, ALT, and platelet count. However, the influence of factors such as Helicobacter pylori (H. pylori) on fibrosis tests such as APRI and FIB-4 remains unclear, and this study aimed to evaluate its impact.