MASASHİ KADOHİSA, YUKİHİRO INOMATA, KEİTA SHİMATA, KAORİ ISONO, MASAKİ HONDA, SHİNTARO HAYASHİDA, YUKİ OHYA, HİDEKAZU YAMAMOTO, HİDEAKİ OKAJİMA, TAİZO HİBİ
Experimental and Clinical Transplantation - 2024;22(3):223-228
Objectives: Donor safety is paramount in living donor liver transplantation. However, there remains a risk of postoperative complications for some donors. Here, we provide a comprehensive assessment of donor morbidity by a single team with 17 years of experience at a single center. Materials and Methods: We retrospectively reviewed 453 donor hepatectomies of living donor liver transplants at Kumamoto University from August 2000 to March 2017. Posterior segment graft cases were excluded in this study. Results: The donors were classified by graft type as follows: right lobe (n = 173), left lobe (n = 149), and left lateral segment (n = 131). The overall complication rate was 29.8%, and the severe complication (Clavien-Dindo grade IIIa or higher) rate was 9.1%. The most frequent complication was bile leakage, with an overall incidence of 13.9% and severe incidence of 4.6%. Among the 3 types of graft, there were no significant differences in bile leakage with any Clavien-Dindo grade. However, upper gastrointestinal complications, such as a duodenal ulcer and gastric stasis, were related to left lobe donation. Conclusions: There were no significant differences in the incidence of postoperative donor complications, except upper gastrointestinal complications, among the 3 types of graft.
