Özge Çetinarslan, Fatih Mehmet Uçar, Selen Yurdakul
Demiroğlu Bilim Üniversitesi Florence Nightingale Tıp Dergisi - 2025;11(2):92-96
Secondary mitral regurgitation (SMR) aggravates prognosis in heart failure with reduced ejection fraction, particularly when guideline-directed medical therapy (GDMT) fails. Transcatheter edge-to-edge repair (TEER) has emerged as a viable option for high-risk surgical candidates. Herein, we report the case of a 77-year-old male with end-stage non-ischemic dilated cardiomyopathy and severe SMR who experienced five decompensations in three months despite optimal GDMT. This case illustrates that in select patients with advanced heart failure and severe SMR, TEER may provide meaningful symptomatic and hemodynamic improvement when surgical or mechanical circulatory support is not feasible. Key determinants of success included precise anatomic selection, preprocedural optimization with levosimendan and natriuresis-guided diuresis, and structured follow-up. TEER, when integrated into a multidisciplinary care pathway, offers more than palliation-it can help stabilize disease and preserve quality of life.
