MEHMET VELİDEDEOGLU, OZAN AKINCI, BAŞAR CAN TURGUT, YASEMİN PEKMEZCİ, BİLGUL METE, OSMAN ŞİMŞEK, KAYA SARİBEYOGLU, SALİH PEKMEZCİ
Southern Clinics of Istanbul Eurasia - 2022;33(3):304-309
INTRODUCTION: Although preoperative biliary stenting (PBS) restores enterohepatic circulation during the preoperative period, its postoperative outcomes remain unclear. This study aimed to evaluate the effects of PBS on bacterial colonization in bile fluid and postoperative morbidity and mortality rate for pancreatic surgery. METHODS: A total of 70 patients who underwent pancreaticoduodenectomy due to periampullary tumor between January 2016 and May 2020 were analyzed retrospectively. Patients were divided into PBS and non-PBS groups. Intraoperative and postoperative outcomes were compared between the two groups. Results: The rate of positive growth in bile culture was significantly higher in the PBS group (89.2%) compared with the non-PBS group (9.5%) (p<0.001). The rates of postoperative infectious complications were found to be 85.7% and 28.5% in PBS and non-PBS groups, respectively (p<0.001). In the PBS group, the rate of postoperative complications increased with the time interval between stenting and surgery (p=0.007). There were no significant differences in both groups in terms of length of hospital stay and postoperative mortality (p=0.186 and p=0.294, respectively). DISCUSSION AND CONCLUSION: Biliary stenting before pancreaticoduodenectomy increases the complications such as bacterial colonization in bile fluid, postoperative wound site infection, and intra-abdominal abscess. The prolonged time between PBS and surgery increases the rate of postoperative infectious complications.
