BULENT EMRE BILGIC, ENİS OZKAYA, CİGDEM YAYLA ABIDE, SEMRA KAYATAS ESER, ILHAN SANVERDI, TAYFUN KUTLU
Gynecology Obstetrics & Reproductive Medicine - 2019;25(1):22-27
OBJECTIVE: The objective of this study was to investigate the effect of total or partial assisted hatching on the clinical pregnancy rates in assisted reproduction technology. STUDY DESIGN: This was a case-control study conducted from the beginning of January 2016 to the end of June 2017. A total of 404 cycles were included in this case-control study. Study population was divided into 3 groups: Group 1: Partial assisted hatching (n=118), Group 2: Total assisted hatching (n=81) and Control group (n=205). RESULTS: In women of all ages, clinical pregnancy rates were similar between groups with total or partial assisted hatching compared to control group (p>0.05). The rates were also similar in subgroups of women with blastocyst or cleavage stage embryo transfers (p>0.05). Partial or total embryo hatching did not result in favorable outcome compared to the control group either in women over 35 or younger than 35 years of age (p>0.05). In whole study group, pregnancy rate was significantly higher in the group with blastocyst stage embryo transfers (22.4 % versus 48.8%, p<0.05). CONCLUSION: Partial or total assisted hatching do not have any impact on the clinical pregnancy rates, no significant impact was determined in the subgroup of women either.
