Asude FENKCI, İbrahim Veysel FENKCI
Eurasian Clinical and Analytical Medicine - 2026;14(2):43-47
Electromagnetic fields (EMFs), either in physical or biological systems, can be found in cells via charge movement, membrane potentials, and molecular dipoles. Although their influences on processes like proliferation and signaling are being studied more frequently, interactions with nucleic acids are less well-defined. According to this hypothesis, the DNA's natural electromagnetic properties might act on transcriptional regulation through dipole interactions in base pairs. For example, the ordered hydrogen bonds from A,T,G, and C in the DNA helix could form localized electromagnetic patterns that may control conformational dynamics or transcription mechanisms. Such effects could provide an additional layer of regulation, working in synergy with classical epigenetic signals. To this end, here we present a conceptual framework and experimental design to test whether EMF exposure in a controlled manner can modulate transcriptional efficiency or protein expression independent of DNA sequence. If they prove to be accurate, such discoveries could offer important new information on the regulation of gene activity, epigenetic responses to environmental stress, and adaptation during the evolution of species.
