MUHAMMED GAZİ YİLDİZ, DOGAN CAKAN
Eurasian Journal of Medical Investigation - 2021;5(2):263-268
Objectives: The aim of this study was to invastigate the relation between positron emission tomography/computed tomography(PET/CT) and postoperative pathology findings in larynx cancer. Methods: Fifty patients with larynx cancer were included in the study.The SUVmax values and dimensions of larynx(Mass-SUVmax) and neck lymph nodes(Node-SUVmax) were measured by PET/CT.The specimens were exam ined pathologically, and the relationship between preoperative PET/CT values and pathology findings of the tumor was examined. Results: The mean age of the patients with lymph node metastasis(65.71±9.20 years) was statistically significantly higher than the patients without lymph node metastasis(60.46±8.72 years)(p<0.05).PET/CT(Mass-SUVmax and Node SUVmax) levels were found to be significantly higher in patients with lymph node metastasis compared to patients without metastasis(p<0.05). The DFS was found longer than 5 years in 64.0% (n=32) of the patients.A statistically sig nificant relationship was found between the presence of lymph node metastasis and DFS.DFS was found to be shorter in patients with lymph node metastasis(p<0.05).The PET-CT(Node-SUVmax) levels were found to be statistically signifi cantly higher in the poorly differentiated group compared to the well-differentiated group(p<0, 05). Conclusion: In our study, we showed that cervical lymph node metastasis was associated with short DFS in patients with larynx cancer, and high PET/CT levels and poor differentiation were associated with lymph node metastasis.
