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EVALUATION OF THE ANTIOXIDATIVE AND PROTECTIVE EFFECTS OF THYMOQUINONE IN A PENTYLENETETRAZOLE-INDUCED EPILEPSY MODEL

MUKADDES PALA, İSMAİL MERAL, NİLGÜN PALA AÇIKGÖZ, FERHAT HANİKOĞLU, İKBAL ÖZEN KÜÇÜKÇETİN, SEBAHAT ÖZDEM, ŞENAY GÖRÜCÜ YILMAZ

Archives of Epilepsy - 2025;31(1):6-12

Malatya Turgut Özal University Faculty of Medicine, Department of Physiology, Malatya, Türkiye

 

Objective: Epilepsy is a common neurological disorder that leads to neuronal excitability and provokes various forms of cellular reorganization in the brain. We investigated the antioxidative and protective effects of thymoquinone (TQ) from the perspective of biomarkers in serum samples of rats using a pentylenetetrazol (PTZ)-induced epilepsy model.