PINAR BİROL İLTER, MEHMET METE KIRLANGIÇ, BATUHAN ÇAĞLAR, ALİ İLTER
Southern Clinics of Istanbul Eurasia - 2024;35(4):306-310
Objective: Pelvic organ prolapse (POP) is a common condition; however, it is rarely observed to affect renal functions and cause hydronephrosis. In our study, we aimed to evaluate these effects of POP. Methods: In this retrospective study, patients who underwent anti-prolapse surgery due to POP were included as the case group, and those who underwent hysterectomy for non-POP indications were included as the control group between January 1 and July 1, 2024. Renal function blood parameters (urea, creatinine, blood urea nitrogen [BUN], glomerular filtration rate [GFR], and uric acid values) were compared between the control and POP groups. Preoperative urinary system ultrasonography (US) data were also analyzed. Results: Patients were included in the POP group and the control group (N1=N2=187). The groups were statistically similar and homogeneous in terms of age (p=0.678) and comorbidities (p=0.872). The number of patients with values outside laboratory cut-off values was 8, 17, 51, 16, and 15 patients in the POP group for creatinine, uric acid, GFR, urea, and BUN, respectively. GFR (p<0.001), urea (p=0.005), and BUN (p=0.008) values showed statistically significant differences between the two groups. When renal function tests were analyzed according to POP grades, no significant differences were detected for any parameter between grades 2, 3, and 4. Hydronephrosis was detected in 9 patients (16.4%) in the POP group evaluated with urinary US. Conclusion: We determined that lower GFR, and higher BUN and urea values were present in the prolapse group. Although it is believed that this condition may regress after POP surgery, data supporting this could not be obtained due to the retrospective nature of the study
