EMİNE TATAR, İSMET REZANİ TOPTANCI
International Dental Research - 2019;9(3):138-144
Aim: The goal of this particular research was to scrutinize the remineralization effects of fluoride varnish, casein phosphopeptide amorphous calcium phosphates (CPP-ACP) and casein phosphopeptide amorphous calcium fluoride phosphates (CPP-ACFP) cream, and tricalcium phosphate (TCP) varnish. Methodology: The study was designed as an experimental research whereby samples with early artificial caries lesions were randomly divided into the following 5 groups with 20 samples in each group: (I) control, (II) fluoride varnish, (III) CPP-ACP cream, (IV) CPP-ACFP cream and (V) TCP varnish. The effectiveness of these remineralization agents was evaluated using a laser fluorescence device (DIAGNOdent), a scanning electron microscope (SEM) and energy dispersive X-ray analysis (EDX). Results: In the pre- and post-treatment evaluations, the DIAGNOdent remineralization measurements were statistically significant in all the groups, except the control group (p < 0.05). In comparison with the DIAGNOdent measurements, the CPP-ACFP group was found to have significantly higher remineralization than the fluoride group (p < 0.05), while no significant differences were found between the other groups (p > 0.05). The EDX analysis evaluated the Ca/P ratio between the groups. These results indicated that the CPP-ACFP group was significantly higher than the control group, the CPP-ACP group and the TCP group (p < 0.05); no significant differences were found between the CPP-ACFP group and the fluoride group (p > 0.05). In SEM imaging, the most extensive mineral accumulation was observed in the CPP-ACFP group. Conclusions: Three analytical methods demonstrated that CPP-ACFP was the most effective remineralization material tested in this study.
