Adnan HOCAOĞLU, Muhammet Esat KARADUMAN, Mustafa SABAK, Şevki Hakan EREN
European Journal of Therapeutics - 2026;32(2):182-190
Objective: The determination to end cardiopulmonary resuscitation (CPR) rests upon the administering physician, who considers a multitude of factors, including witnessed or unwitnessed arrest, duration of CPR, initial arrest rhythm, duration of defibrillation, comorbidities, pre-arrest status, and whether or not spontaneous circulation (ROSC) was achieved during resuscitation. Methods: This was a single-center, prospective and observational study. The research included patients who experienced in-hospital (IHCA) and out-of-hospital cardiopulmonary arrest (OHCA). The Bispectral index (BIS) value, which is a scored assessment between 0 and 100, was recorded at 10-minute intervals from the start of CPR. The BIS value at the time of death or ROSC was recorded and the procedure was terminated Results: A total of 25 patients were included and ROSC was achieved in 9 (36%). The mean age of the patients was 64.6 years and 50% had comorbid diseases. Most patients (64%) were brought to the emergency department by an Emergency Medical Technician (EMT). The initial BIS value at the time of initiation of CPR was 35.19 +/-14.49 vs 30.44 +/-13.13 in patients who died and those who received ROSC, respectively; the BIS value at the time of death decision and ROSC was 34.06 vs 36.56 Conclusion: This study concluded that BIS monitoring is not be sufficient in determining the prognosis of patients with cardiac arrest and guiding decision on terminate of resuscitation.
