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EVALUATION OF TREATMENT RESPONSES WITH PRE- AND POST-TREATMENT DENSITY MEASUREMENT VALUES OF BREAST CANCER IN THORAX CT

TULİN OZTURK

Eurasian Journal of Medical Investigation - 2022;6(3):312-317

Department of Radiology, Medical Park Hospital, Elazığ, Türkiye

 

Objectives: We aimed to investigate the contribution of mass CT density values to the diagnosis in the evaluation of the response of the local disease to the treatment during the treatment of breast cancer. Methods: 40 female patients histopathologically proven to have breast cancer, had routine Thorax CT at diagnosis and the treatment stage, and whose metabolic activity was known by PET CT were included.The mean mass densities were measured from malignant breast lesions at the time of diagnosis and after treatment through the Thorax CT examinations. Results: In our study, we found the mean mass density measurement values of breast cancer before treatment as 38.21 HU, and the average density measurement values after treatment as 20.54 HU. We showed that malignant mass densi ties were significantly reduced in the non-metabolic period after treatment. We found that thorax CT density values can be a guide in evaluating the response of malignant breast lesions to local treatment. Conclusion: In conclusion, adding a quantitative CT attenuation value to breast lesions examinations increases the diagnostic accuracy of malignant lesions. We have shown that malignant lesions show significantly higher attenuation on Thorax CT and attenuation values decrease in response to treatment.