Qianwei SANG, Qian ZHAO, Linji WU
Psychiatry and Clinical Psychopharmacology - 2026;36(4):441-450
Background: Perioperative anxiety is common in women undergoing surgery for ectopic pregnancy and may aggravate pain and delay recovery. This trial evaluated whether evidence-based nursing combined with structured psychological intervention reduces perioperative anxiety compared with routine nursing in women undergoing conservative laparoscopic surgery for tubal ectopic pregnancy. Methods: In this single-center, parallel-group randomized controlled trial, 124 women with tubal ectopic pregnancy scheduled for non-emergency conservative laparoscopic surgery were enrolled by convenience sampling and randomly assigned 1:1 to a control group (routine perioperative nursing) or an experimental group (evidence-based nursing plus structured psychological intervention). The prespecified primary outcome was the between-group difference in State Anxiety Inventory (S-AI) score on the day of discharge. Secondary outcomes were postoperative pain (Visual Analogue Scale, VAS) and short-term recovery outcomes. Results: The day-of-discharge S-AI score was lower in the experimental group than in the control group (32.61 +/- 4.45 vs 38.24 +/- 2.62; mean difference -5.63, 95% CI -6.92 to -4.34; P < .001), with a significant group-by-time interaction (P < .001). VAS scores at 2, 6, 12, and 24 hours after surgery were lower in the experimental group (all P < .001). First ambulation time, length of hospital stay, antibiotic use time, and menstrual recovery time were shorter in the experimental group (all P < .001). Conclusion: Evidence-based nursing combined with structured psychological intervention was associated with lower perioperative anxiety and postoperative pain and with shorter short-term recovery outcomes in women undergoing conservative laparoscopic surgery for tubal ectopic pregnancy.
