MÜZEYYEN AYBÜKE YAYLA, OYTUN ERBAŞ
Demiroğlu Bilim Üniversitesi Florence Nightingale Tıp Dergisi - 2024;10(1):26-33
Obesity is a disease that develops as a result of multifactorial causes such as genetic, environmental, biological, psychosocial, and economic factors, leading to excessive fat accumulation and a body mass index exceeding 30 kg/m2. In our bodies, there are appetite-stimulating and suppressing hormones that regulate nutrient intake and control energy metabolism, either directly secreted or via the hypothalamus. This review examines the relationships between obesity and major appetite-suppressing hormones, including the protein-based leptin hormone synthesized from adipose tissue and nesfatin-1, a neurohormone expressed from adipose tissue, pancreas, and brain, as well as ghrelin, a peptide hormone also known as an appetite stimulant.
