FIG SEED OIL INDUCES MITOCHONDRIAL-MEDIATED APOPTOSIS IN HEPG2 CELLS

ADEM YAVAŞ

Süleyman Demirel Üniversitesi Tıp Fakültesi Dergisi - 2025;32(3):230-239

Aydın Adnan Menderes University, Çine Vocational School, Food Quality Control and Analysis Programme, Aydın, Türkiye

 

Objective Hepatocellular carcinoma (HCC) remains a significant global health challenge with limited effective therapies, necessitating the identification of novel therapeutic agents. Fig seed oil (FSO), rich in bioactive compounds, is being explored for its health benefits, including potential anti-cancer effects. This study investigated the cytotoxic, pro-apoptotic (via the mitochondrial pathway), and oxidative stress-modulating effects of FSO on HepG2 cells.