YONGBİNG QİAN, HAOMİN ZHANG, XİAOSONG CHEN, JİANJUN ZHANG, QİANG XİA
Experimental and Clinical Transplantation - 2020;18(4):529-532
Carbapenem-resistant Klebsiella pneumoniae infection is a major cause of morbidity and mortality after solidorgan transplant and hematopoietic stem cell transplant. Here, we report a 57-year-old man with hepatitis B virus-related decompensated liver cirrhosis, huge splenic artery aneurysm, and hypersplenism who underwent liver transplant from a deceased brain-dead donor. Recipient sputum surveillance showed carbapenem-resistant Klebsiella pneumoniae when he entered the intensive care unit, and combined tigecycline, meropenem, and fosfomycin were administered. At 1 week posttransplant, the recipient’s hepatic artery was eroded by disseminated carbapenem-resistant Klebsiella pneumoniae infection, and the patient developed acute kidney injury. Our experience suggests that colonization of carbapenemproducing organisms may be included during surveillance posttransplant and that the infected graft artery must be removed instead of noninfected vessels.
