EMEL EBRU ÖZÇİMEN, AYLA ÜÇKUYU, IŞIK ÜSTÜNER, FİLİZ FATMA YANIK,SEVSEN KULAKSIZOĞLU, MESUT ÖKTEM, DERYA EROĞLU, ESRA KUŞÇU
Gynecology Obstetrics & Reproductive Medicine - 2006;12(3):165-168
OBJECTIVE: To investigate the relationship between Helicobacter pylori (H. pylori) infection and hyperemesis gravidarum (HG) by using H. pylori specific serum antibody test and H. pylori stool antigen (HpSA). MATERIAL AND METHODS: This prospective cross-sectional study was carried out on 70 pregnant women with HG and 70 healthy pregnant women. Serum immunoglobulin G antibody for H. pylori and HpSA were assayed in both groups. Chi-square test was used for statistical analysis. RESULTS: The study and control groups were matched regarding the maternal age, gestational weeks, gravida and parity. Positive serum IgG concentrations were found in 35 of the 70 HG patients (50%) compared with 33 of 70 controls (47.1%), (p>0.05). The rate of HpSA positivity was 32.8% (23/70) and 21.4% (15/70) respectively (p>0.05). CONCLUSION: Contradicting with most of the studies which investigated the relationship between H. pylori infection and HG, our results indicate no significant relationship between HG and H. pylori IgG and HpSA.
