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HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS AFTER CERTOLIZUMAB TREATMENT IN A PATIENT WITH RHEUMATOID ARTHRITIS

GÖKSEL GÜVEN, ASLIHAN GÜLER, NİL ÖZYÜNCÜ, LEYLA TALAN, AYLİN HEPER, TAHSİN MURAT TURGAY, NERİMAN DEFNE ALTINTAŞ

European Journal of Rheumatology - 2018;5(3):203-205

Department of Internal Medicine, Division of Intensive Care, Ankara University School of Medicine, Ankara, Turkey

 

Hemophagocytic lymphohistiocytosis (HLH) is a rare and life-threatening syndrome that may be triggered by hereditary factors, autoimmune and immunologic disorders, infectious diseases, malignancies and medications. Suspicion of the disease and early treatment is of paramount importance. Since the presentation of HLH with only skin involvement is rare, early diagnosis may be difficult. A pathologically confirmed HLH case that presented with maculopapular skin lesions after certolizumab treatment is being reported in this presentation.