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HEPATITIS C VIRUS IN THE RENAL TRANSPLANT POPULATION: AN UPDATE WITH FOCUS ON THE NEW ERA OF ANTIVIRAL REGIMENS

OSAMA GHEİTH, MEDHAT A HALİM, NASHWA OTHMAN, TORKİ AL-OTAİBİ, PRASAD NAİR, NARYANAN NAMPOORY

Experimental and Clinical Transplantation - 2017;15(1):10-20

Urology and Nephrology Center, Mansoura University, Mansoura, Egypt

 

Chronic hepatitis C virus infection is a global health problem, especially among renal transplant recipients. Herein, we present an overview of hepatitis C virus among renal transplant patients, with a focus on some updated aspects concerning types of viral genotypes, methods of diagnosis, the effects of renal transplant on hepatitis C virus infection, and summary of hepatitis C virus-related complications after renal transplant. We also discuss patient and graft survival rates and the present and future therapeutic options with special focus on new antiviral and possible interactions with immunosuppressive medications.