VEDAT ÖZTÜRK, MUSTAFA YALIN
Medical Journal of Bakırköy - 2025;21(2):221-224
Necrotizing fasciitis is a rare, life-threatening soft tissue infection that is infrequently associated with sigmoid colon perforation, particularly following high-dose radiation therapy (RT) for cervical cancer. This case report presents a 58-year-old female patient with advanced cervical cancer treated with RT. She presented with general deterioration and left lumbar pain. Imaging studies revealed gas in the left hip and thigh, and extraluminal leakage suggestive of bowel perforation. Emergency laparotomy and surgical debridement confirmed a sigmoid colon perforation with stool contamination extending into the thigh. Despite aggressive interventions, including partial colon resection and fasciotomy, the patient succumbed to sepsis and multi-organ failure within 24 hours. This case highlights the rare but serious complication of necrotizing fasciitis secondary to radiation-induced sigmoid colon perforation, emphasizing the importance of early diagnosis and timely intervention.
