SERDAR DİLBAZ, ÖZLEM ÖZDEĞİRMENCİ, BERNA DİLBAZ, YASEMİN TAŞÇI, EMİNE SEDA GÜVENDAĞ GÜVEN, ALİ HABERAL, AHMET ÖZFUTTU
Gynecology Obstetrics & Reproductive Medicine - 2006;12(1):20-22
OBJECTIVE: To evaluate the endometrial changes in patients with proven ectopic pregnancies and the value of endometrial histopathology in diagnosis of ectopic pregnancies. STUDY DESIGN: Medical records of 71 patients with proven ectopic pregnancies and who had endometrial curettage results were reviewed. Ectopic pregnancy was confirmed either at operation or at transvaginal ultrasound evaluation with clearly visualized characteristic adnexal mass in the presence of an empty uterus and serum beta-subunit human chorionic gonadotropin level above the discriminatory zone. Histopathologic findings of the endometrial curettage materials were evaluated. RESULTS: The mean age of the patients was 30±5.9 years. The mean gestational age (by date of last menstrual period) at presentation was 36.9 days. The most common symptoms at presentation were both vaginal bleeding and missed menstruation. Review of the endometrial curettages revealed that the most common type of endometrium associated with ectopic pregnancy was secretory (52.2%) followed by decidual reaction (15.5%), proliferative endometrium (14.1%), Arias-Stella reaction (11.2%), and endometrial fragments (7%). CONCLUSION: Since ectopic pregnancy is associated with various types of endometrial histopathology, it is not valuable in the diagnosis and should be performed in selected patients for differential diagnosis when TVUS, serial serum b-HCG levels are inconclusive.
