SİDDİKA SONGUL YALCİN, B BARİS KUSKONMAZ, VİCENTE PEREZ BROCAL, DUYGU UCKAN CETİNKAYA, ANDRES MOYA, ENER CAGRİ DİNLEYİCİ
Experimental and Clinical Transplantation - 2024;22(9):726-729
Following primary infection, human mastadeno-viruses can persist in various tissues. We report a case of a pediatric patient with Fanconi anemia who had a complicated posttransplant course after allogeneic hematopoietic stem cell transplant that was associated with human mastadenovirus infection. Human mastadenovirus reactivation was detected with metagenomic analysis during a 3-month follow-up period; the predominant rate of occurrence of human mastadenoviruses was 1.1% on day 0, 84% on day +15, 90% on day +30, and 42% on day +82. Virus shedding continued up to 3 months after transplant. At 36 months after hematopoietic stem cell transplant, the patient was in good clinical condition with full donor chimerism. Long-term follow-up studies for human mastadenoviruses are needed to determine latency period.
