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ADR Yönetimi

HYDROGEL SPACER MAY ALLOW PROSTATE RE-IRRADIATION EVEN IN PATIENTS WITH ULCERATIVE COLITIS: A CASE REPORT

MARİANGELA MASSACCESI, LUCA TAGLIAFERRI, LUCİA CERVONE, ANTONİO PIRAS, SEBASTİANO MENNA, LUİGİ AZARİO, GİAN CARLO MATTIUCCI, PATRİZİA CORNACCHIONE, VALENTİNA LANCELLOTTA, MARİA ANTONIETTA GAMBACORTA, VİNCENZO VALENTINI

Turkish Journal of Oncology - 2020;35(1):87-92

Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome-Italy

 

Salvage radiotherapy is a valid option for locally recurrent prostate cancer (PC) patients. Two of the treatment options are as follows: interventional radiotherapy or stereotactic body radiotherapy (SBRT). SBRT has the main advantage as a noninvasive procedure. Synthetic gel injection into the prostate and rectum space, as a novel technique in prostate radiotherapy, spares the anterior rectal wall from a high dose. Inflammatory bowel disease, including Crohn’s disease and ulcerative colitis (UC), contraindicate external beam radiotherapy due to increased bowel complication risk. In this study, we describe the first PC patient with UC in remission treated with salvage SBRT and hydrogel rectal spacer. After ten months of follow-up, no bowel symptoms were reported, and SBRT provided both biochemical and clinical response. Even patients with UC and radio-recurrent PC may be viable salvage SBRT candidates.