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ADR Yönetimi

IMAGING FEATURES AND HISTOPATHOLOGICAL ANALYSIS IN PATIENTS WITH SUBCENTIMETER BREAST CANCER DETECTED BY ULTRASONOGRAPHY

NURDAN FİDAN, CUNEYT YUCESOY, ZEYNEP BANU AYDIN, UNSAL HAN, BETUL BOZKURT

Eurasian Journal of Medical Investigation - 2022;6(3):304-311

Department of Radiology, Faculty of Medicine, Hitit University,Corum, Turkey

 

Objectives: We aimed to present preoperative ultrasonographic features, distribution of histopathological diagnosis and molecular subtypes of malignant tumors, and to compare sonographic and pathological tumor dimensions in patients with subcentimeter breast lesions. Methods: Eighty six women with newly diagnosed breast cancer were included in the study who underwent preopera tive biopsy and surgical resection between 2015 and 2020. Sonographically tumor margins were grouped as circum scribed, microlobulated, irregular-indistinct, angular and spiculated. By taking 25% of the pathological tumor size and value of ± 5 mm as cut-off, the presence of sonopathological concordance was evaluated. Results: The median tumor sizes were 10 mm (4-10 mm) sonographically and 11 mm (2-45 mm) histopathologically. The spiculated and irregular-indistinct margins were the most frequent sonog-raphic features (35% and 35%). Value of ±5 mm and 25% of the pathological tumor size acording to cut-off, the sonopathological concordance rates were calculated as 74% and 55%, the underestimation rates were 20% and 35%, the overestimation rates were 6% and 10%, respectively. Conclusion: In our study, the most common sonographic features was spiculated and irregular-indistinct margins. We found sonopathological concordance rates similar to current literature. Especially in patients with DCIS, invasive lobular carcinoma, and HER2 enriched subtype, sonopathological discordance should be considered when planning the optimal treatment.