DİLEK YEĞİN, ŞENİZ KORKMAZ
International Journal of Medical Biochemistry - 2025;8(3):192-198
Objectives: Persistent overactivation of inflammatory responses has been associated with various neurodegenerative disorders, including Alzheimer disease. This study aimed to investigate whether parameters derived from complete blood count, such as white blood cell populations, platelet counts, and hemogram-derived parameters like platelet-lymphocyte ratio, immature granulocyte-lymphocyte ratio, systemic immune-inflammation index, and platelet-neutrophil ratio, which can be easily detected without additional cost, could have diagnostic value in the pathogenesis of Alzheimer disease. Additionally, the co-occurrence rates of Alzheimer disease with other diseases (such as Parkinson disease, anxiety, diabetes mellitus, cancer, osteoporosis and kidney disease) were analyzed.
