RENJİNİ DEVİ MR, SHEHNAZ SULTANA, SHELVY SREEKUMAR, VENKATESHWARİ ANANTHAPUR
International Journal of Medical Biochemistry - 2025;8(2):99-106
Objectives: Recurrent spontaneous abortion (RSA) is the successive loss of pregnancy experienced by 1-2% of women with clinically recognized pregnancies. The role of cytokines and their regulators in RSA has gained significant attention in recent years. The GATA3 transcription factor has significant implications for maternal-foetal health outcome by modulating the immune T-cell population to T helper cell subsets that produce the proinflammatory (IFNγ) and anti-inflammatory cytokines (IL4) required for pregnancy maintenance.
